Formononetin inhibits human bladder cancer cell proliferation and invasiveness via regulation of miR-21 and PTEN

The isoflavone formononetin is the main active component of Astragalus membranaceus and possesses anti-tumorigenic properties. However, the role of formononetin in human bladder cancer (BCa) has not been fully elucidated. The aim of the present study was to investigate the anti-tumor effects of form...

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Veröffentlicht in:	Food & function 2017-03, Vol.8 (3), p.161-166
Hauptverfasser:	Wu, Yiying, Zhang, Xing, Li, Zhengzhao, Yan, Haibiao, Qin, Jian, Li, Tianyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Astragalus Astragalus Plant - chemistry Cell Proliferation - drug effects Drugs, Chinese Herbal - pharmacology Humans Isoflavones - pharmacology MicroRNAs - genetics MicroRNAs - metabolism Neoplasm Invasiveness PTEN Phosphohydrolase - genetics PTEN Phosphohydrolase - metabolism Urinary Bladder Neoplasms - drug therapy Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - physiopathology
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