Ni(0)–Cu( i ): a powerful combo catalyst for simultaneous coupling and cleavage of the C–N bond with cyclization to valuable amide-based pyrroles and 4-pyridones

Ni(0)–Cu( i ): a powerful combo catalyst for simultaneous coupling and cleavage of the C–N bond with cyclization to valuable amide-based pyrroles and 4-pyridones

Unprecedented ligand-tuned Ni(0)–Cu( i ) combo catalysis is demonstrated via sequential bond activated domino C–N/C–C coupled annulation with C–N bond cleavage to afford valuable polysubstituted amide-based pyrroles and 4-pyridones selectively from β-ketoanilides.

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Veröffentlicht in:RSC advances 2015-01, Vol.5 (90), p.73346-73351
Hauptverfasser: Roy, Dipanwita, Sarkar, Satinath, Laha, Radha M., Pramanik, Nabyendu, Maiti, Dilip K.
Format: Artikel
Sprache:eng
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Zusammenfassung:Unprecedented ligand-tuned Ni(0)–Cu( i ) combo catalysis is demonstrated via sequential bond activated domino C–N/C–C coupled annulation with C–N bond cleavage to afford valuable polysubstituted amide-based pyrroles and 4-pyridones selectively from β-ketoanilides.
ISSN:2046-2069
2046-2069
DOI:10.1039/C5RA12115A