Calcinated gold nanoparticle arrays for on-chip, multiplexed and matrix-free mass spectrometric analysis of peptides and small molecules

A patterned gold nanoparticle microarray, functionalized with a nanoscale silicate coating, has been developed for on-chip, high-throughput mass spectrometric analyses of biomolecules with minimal sample preparation and reagent costs. Fabrication was realized by the combination of layer-by-layer fun...

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Veröffentlicht in:	Nanoscale 2016-01, Vol.8 (3), p.1665-1675
Hauptverfasser:	Hinman, Samuel S, Chen, Chih-Yuan, Duan, Jicheng, Cheng, Quan
Format:	Artikel
Sprache:	eng
Schlagworte:	Arrays Biomolecules Coating Gold Gold - chemistry Ionization Mass Spectrometry - methods Metal Nanoparticles - chemistry Multiplexing Nanostructure Peptides - analysis Protein Array Analysis - methods Spectroscopy
Online-Zugang:	Volltext
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