Binding of a potential anti-hepatoma drug cis,cis,trans-[Pt(NH 3 ) 2 Cl 2 (O 2 CCH 2 CH 2 COOH)-(OCONHC 16 H 33 )] with serum albumin – thermodynamic and conformational investigations

In this paper, a potential anti-hepatoma Pt 4+ drug cis , cis , trans -[Pt(NH 3 ) 2 Cl 2 (O 2 CCH 2 CH 2 COOH)-(OCONHC 16 H 33 )] was synthesized and selected to investigate its binding to human serum albumin (HSA) by spectroscopy and molecular docking methods. Fluorescence spectra show that the Trp...

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Veröffentlicht in:	New journal of chemistry 2015-01, Vol.39 (12), p.9234-9241
Hauptverfasser:	Qi, Li, Lu, Zhong, Lang, Wen-hua, Guo, Lu, Ma, Chang-geng, Sun, Guang-hong
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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