Design and synthesis of peptide inhibitor conjugates as probes of the Cytochrome P450s from glycopeptide antibiotic biosynthesis

The glycopeptide antibiotics are important clinical antibiotics that are currently employed against serious Gram-positive bacterial infections. Their chemical complexity means that their production is reliant upon the natural biosynthesis pathway, of which the key steps are the synthesis and side ch...

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Veröffentlicht in:MedChemComm 2016-01, Vol.7 (1), p.132-14
Hauptverfasser: Brieke, Clara, Maier, Theresa, Schröter, Martin, Cryle, Max J
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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