N-Phosphonyl/phosphinyl imines and group-assisted purification (GAP) chemistry/technology
The development of environmentally benign, operationally simple, and economically viable synthetic methodologies has been a great challenge in organic synthesis. Group-assisted purification (GAP) chemistry was established to enable the synthesis of organic compounds without using traditional purific...
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| Veröffentlicht in: | Organic & biomolecular chemistry 2015-02, Vol.13 (6), p.1600-1617 |
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| container_title | Organic & biomolecular chemistry |
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| creator | An, Guanghui Seifert, Cole Li, Guigen |
| description | The development of environmentally benign, operationally simple, and economically viable synthetic methodologies has been a great challenge in organic synthesis. Group-assisted purification (GAP) chemistry was established to enable the synthesis of organic compounds without using traditional purification technologies, such as column chromatography and recrystallization. This concept/technology should encourage the synthetic community to make more efforts on searching for environmentally benign reagents and reactions to reduce the waste generated from silica and solvents, particularly toxic solvents; also, to reduce production/synthesis expenses, manpower, and energy. This review will discuss the GAP concept/technology and related reactions that were mainly conducted in the PI's laboratories after 2010. |
| doi_str_mv | 10.1039/c4ob02254h |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1477-0520 |
| ispartof | Organic & biomolecular chemistry, 2015-02, Vol.13 (6), p.1600-1617 |
| issn | 1477-0520 1477-0539 |
| language | eng |
| recordid | cdi_crossref_primary_10_1039_C4OB02254H |
| source | MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Imines - chemistry Imines - isolation & purification Molecular Structure Organophosphorus Compounds - chemistry Organophosphorus Compounds - isolation & purification |
| title | N-Phosphonyl/phosphinyl imines and group-assisted purification (GAP) chemistry/technology |
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