Effects of PEGylated paclitaxel nanocrystals on breast cancer and its lung metastasis

As an attractive strategy developed rapidly in recent years, nanocrystals are used to deliver insoluble drugs. PEGylation may further prolong the circulation time of nanoparticles and improve the therapeutic outcome of drugs. In this study, paclitaxel (PTX) nanocrystals (PTX-NCs) and PEGylated PTX n...

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Veröffentlicht in:	Nanoscale 2015-06, Vol.7 (24), p.179-18
Hauptverfasser:	Zhang, Hua, Hu, Hongxiang, Zhang, Haoran, Dai, Wenbing, Wang, Xinglin, Wang, Xueqing, Zhang, Qiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Agents, Phytogenic - chemistry Breast Neoplasms - drug therapy Breast Neoplasms - pathology Cell Line, Tumor Diffusion Humans Lung Neoplasms - drug therapy Lung Neoplasms - pathology Lung Neoplasms - secondary Mice Mice, Nude Nanocapsules - chemistry Nanocapsules - ultrastructure Paclitaxel - administration & dosage Paclitaxel - chemistry Particle Size Polyethylene Glycols - chemistry Treatment Outcome
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