Strategies for the intracellular delivery of nanoparticles
The ability to target contrast agents and therapeutics inside cells is becoming important as we strive to decipher the complex network of events that occur within living cells and design therapies that can modulate these processes. Nanotechnology researchers have generated a growing list of nanopart...
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| Veröffentlicht in: | Chemical Society reviews 2011-01, Vol.4 (1), p.233-245 |
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| creator | Chou, Leo Y. T Ming, Kevin Chan, Warren C. W |
| description | The ability to target contrast agents and therapeutics inside cells is becoming important as we strive to decipher the complex network of events that occur within living cells and design therapies that can modulate these processes. Nanotechnology researchers have generated a growing list of nanoparticles designed for such applications. These particles can be assembled from a variety of materials into desirable geometries and configurations and possess useful properties and functionalities. Undoubtedly, the effective delivery of these nanomaterials into cells will be critical to their applications. In this
tutorial review
, we discuss the fundamental challenges of delivering nanoparticles into cells and to the targeted organelles, and summarize strategies that have been developed to-date.
Development of intracellular delivery strategies for nanoparticles is important to their applications in imaging, bio-sensing, and therapeutics. Here we highlight the current state-of-the-art in delivery strategies and challenges. |
| doi_str_mv | 10.1039/c0cs00003e |
| format | Article |
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tutorial review
, we discuss the fundamental challenges of delivering nanoparticles into cells and to the targeted organelles, and summarize strategies that have been developed to-date.
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tutorial review
, we discuss the fundamental challenges of delivering nanoparticles into cells and to the targeted organelles, and summarize strategies that have been developed to-date.
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tutorial review
, we discuss the fundamental challenges of delivering nanoparticles into cells and to the targeted organelles, and summarize strategies that have been developed to-date.
Development of intracellular delivery strategies for nanoparticles is important to their applications in imaging, bio-sensing, and therapeutics. Here we highlight the current state-of-the-art in delivery strategies and challenges.</abstract><cop>England</cop><pmid>20886124</pmid><doi>10.1039/c0cs00003e</doi><tpages>13</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0306-0012 |
| ispartof | Chemical Society reviews, 2011-01, Vol.4 (1), p.233-245 |
| issn | 0306-0012 1460-4744 |
| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Contrast agents Cytoplasm - metabolism Drug Carriers - chemistry Endosomes - metabolism Humans Ligands Lists Nanomaterials Nanoparticles Nanoparticles - administration & dosage Nanoparticles - chemistry Nanotechnology Networks Organelles Particle Size Peptides - chemistry Peptides - metabolism Strategy |
| title | Strategies for the intracellular delivery of nanoparticles |
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