Pharmacologically Diverse Antidepressants Rapidly Activate Brain-Derived Neurotrophic Factor Receptor TrkB and Induce Phospholipase-Cγ Signaling Pathways in Mouse Brain

Previous studies suggest that brain-derived neurotrophic factor and its receptor TrkB are critically involved in the therapeutic actions of antidepressant drugs. We have previously shown that the antidepressants imipramine and fluoxetine produce a rapid autophosphorylation of TrkB in the rodent brai...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2007-10, Vol.32 (10), p.2152-2162
Hauptverfasser:	Rantamäki, Tomi, Hendolin, Panu, Kankaanpää, Aino, Mijatovic, Jelena, Piepponen, Petteri, Domenici, Enrico, Chao, Moses V, Männistö, Pekka T, Castrén, Eero
Format:	Artikel
Sprache:	eng
Schlagworte:	Behavioral Sciences Biological and medical sciences Biological Psychology Medical sciences Medicine Medicine & Public Health Neuropharmacology Neurosciences original-article Pharmacology. Drug treatments Pharmacotherapy Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology
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