Renin-stimulated TGF-β1 expression is regulated by a mitogen-activated protein kinase in mesangial cells

Recent evidence indicates that renin itself might be profibrotic, independent of angiotensin II; however, the signaling system by which renin exerts a direct effect is not known. We tested the hypothesis that renin receptor activation, in turn, activates the extracellular-signal regulated kinase 1 a...

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Veröffentlicht in:	Kidney international 2007-07, Vol.72 (1), p.45-52
Hauptverfasser:	Huang, Y., Noble, N.A., Zhang, J., Xu, C., Border, W.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	angiotensin II Biological and medical sciences Fundamental and applied biological sciences. Psychology Medical sciences mesangial cell Nephrology. Urinary tract diseases renin signaling Vertebrates: urinary system
Online-Zugang:	Volltext
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