Estradiol Alters Only GAD 67 mRNA Levels in Ischemic Rat Brain with No Consequent Effects on GABA

The present study tested the hypothesis that estradiol reduces tissue infarction after middle cerebral artery occlusion (MCAO) in estradiol-deficient females by augmenting glutamic acid decarboxylase (GAD) expression and thus activity, leading to increases in γ-amino-butyric acid (GABA) tissue level...

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Veröffentlicht in:Journal of cerebral blood flow and metabolism 2006-04, Vol.26 (4), p.518-526
Hauptverfasser: Joh, Hung-Dong, Searles, Robin V, Selmanoff, Michael, Alkayed, Nabil J, Koehler, Raymond C, Hurn, Patricia D, Murphy, Stephanie J
Format: Artikel
Sprache:eng
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