Stromal Cell-Derived Factor 1α Mediates Neural Progenitor Cell Motility after Focal Cerebral Ischemia

In the adult rodent, stroke induces an increase in endogenous neural progenitor cell (NPC) proliferation in the subventricular zone (SVZ) and neuroblasts migrate towards the ischemic boundary. We investigated the role of stromal cell-derived factor 1α (SDF-1α) in mediating NPC migration after stroke...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2006-01, Vol.26 (1), p.125-134
Hauptverfasser:	Robin, Adam M, Zhang, Zheng G, Wang, Lei, Zhang, Rui L, Katakowski, Mark, Zhang, Li, Wang, Ying, Zhang, Chunling, Chopp, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Fundamental and applied biological sciences. Psychology Medical sciences Neurology Neuropharmacology Neuroprotective agent Pharmacology. Drug treatments Vascular diseases and vascular malformations of the nervous system Vertebrates: nervous system and sense organs
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