Effects of phentermine on striatal dopamine and serotonin release in conscious rats : In vivo microdialysis study

To measure the effects of phentermine, an appetite supressant, on the release of brain dopamine (DA) and serotonin (5-HT) into striatal dialysates of freely moving rats. Microdialysis and high performance liquid chromatography. Unanesthetized rats. Samples collected every 20 min were assayed for bot...

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Veröffentlicht in:	International Journal of Obesity 1998-04, Vol.22 (4), p.325-328
Hauptverfasser:	BALCIOGLU, A, WURTMAN, R. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Appetite Depressants - pharmacology Biological and medical sciences Cohort Studies Corpus Striatum - drug effects Corpus Striatum - secretion Dopamine - metabolism Dopamine - secretion Dose-Response Relationship, Drug Injections, Intraperitoneal Male Medical sciences Microdialysis Miscellaneous Neuropharmacology Perfusion Pharmacology. Drug treatments Phentermine - administration & dosage Phentermine - pharmacology Rats Rats, Sprague-Dawley Serotonin - metabolism Serotonin - secretion Tetrodotoxin - pharmacology
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