The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D–lysophosphatidic acid receptor axis and 5‐HT 1A receptors in rat brain sections
The basic secretagogues, such as compound 48/80 (c48/80) and mastoparans, are widely used histamine‐releasing agents and their mechanism of action is commonly attributed to a direct, receptor‐bypassing property to activate the G i/o class of G proteins. We tested here whether c48/80 could directly s...
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| Veröffentlicht in: | British journal of pharmacology 2009-01, Vol.147 (6), p.596-606 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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