Noradrenaline and extracellular nucleotide cotransmission involves activation of vasoconstrictive P2X 1,3 ‐ and P2Y 6 ‐like receptors in mouse perfused kidney

Nucleotides like ATP and UTP act as potent extracellular signalling molecules. Released from sympathetic nerve endings as cotransmitters of noradrenaline or paracrine from nonexcitatory cells, they activate specific receptors (ion‐gated P2X 1–7 and G‐protein‐coupled P2Y 1,2,4,6,11–15 ). Which of the...

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Veröffentlicht in:British journal of pharmacology 2009-01, Vol.145 (1), p.66-74
Hauptverfasser: Vonend, Oliver, Stegbauer, Johannes, Sojka, Johann, Habbel, Sina, Quack, Ivo, Robaye, Bernard, Boeynaems, Jean‐Marie, Rump, Lars Christian
Format: Artikel
Sprache:eng
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