Antihyperalgesic activity of a novel nonpeptide bradykinin B 1 receptor antagonist in transgenic mice expressing the human B 1 receptor

We describe the properties of a novel nonpeptide kinin B 1 receptor antagonist, NVP‐SAA164, and demonstrate its in vivo activity in models of inflammatory pain in transgenic mice expressing the human B 1 receptor. NVP‐SAA164 showed high affinity for the human B 1 receptor expressed in HEK293 cells (...

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Veröffentlicht in:	British journal of pharmacology 2005-04, Vol.144 (7), p.889-899
Hauptverfasser:	Fox, Alyson, Kaur, Satbir, Li, Bifang, Panesar, Moh, Saha, Uma, Davis, Clare, Dragoni, Ilaria, Colley, Sian, Ritchie, Tim, Bevan, Stuart, Burgess, Gillian, McIntyre, Peter
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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