Comparison of functional profiles at human recombinant somatostatin sst 2 receptor: simultaneous determination of intracellular Ca 2+ and luciferase expression in CHO‐K1 cells

Somatostatin (somatotropin release inhibiting factor; SRIF) acts via five G protein‐coupled receptors (sst 1 –sst 5 ) that modulate multiple cellular effectors. The aim of this study was to compare two functional effects of the human sst 2 receptor stably expressed in CHO‐K1 cells in a single experi...

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Veröffentlicht in:British journal of pharmacology 2009-01, Vol.142 (1), p.150-160
Hauptverfasser: Nunn, Caroline, Cervia, Davide, Langenegger, Daniel, Tenaillon, Laurent, Bouhelal, Rochdi, Hoyer, Daniel
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Sprache:eng
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