Gamma-hydroxybutyric acid for treatment of opiate withdrawal syndrome

In a double-blind placebo-controlled trial, gamma-hydroxybutyric acid (GHB) (25 mg/kg orally) suppressed most of the withdrawal symptomatology in 14 heroin addicts and 13 methadone-maintained subjects. The GHB effect was prompt (within 15 minutes) and persisted for between 2 and 3 hours. Subsequentl...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 1993-08, Vol.9 (1), p.77-81
Hauptverfasser:	GALLIMBERTI, L, CIBIN, M, PAGNIN, P, SABBION, R, PANI, P. P, PIRASTU, R, FERRARA, S. D, GESSA, G. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Double-Blind Method Drug addictions Heroin Dependence - psychology Heroin Dependence - rehabilitation Humans Male Medical sciences Methadone - therapeutic use Naloxone Sodium Oxybate - therapeutic use Substance Withdrawal Syndrome - drug therapy Substance Withdrawal Syndrome - psychology Toxicology
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