Genetic analysis of ozone-induced acute lung injury in sensitive and resistant strains of mice

Epidemiological studies have found air pollution to be associated with excessive mortality, particularly death from respiratory and cardiovascular causes 1,2 . Interpretation of these findings is controversial, however, because toxicological mechanisms controlling mortality are uncertain. Susceptibi...

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Veröffentlicht in:	Nature genetics 1997-12, Vol.17 (4), p.471-474
Hauptverfasser:	Prows, Daniel R., Shertzer, Howard G., Daly, Mark J., Sidman, Charles L., Leikauf, George D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Animal Genetics and Genomics Animals Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Chemical and industrial products toxicology. Toxic occupational diseases Classical genetics, quantitative genetics, hybrids Crosses, Genetic Disease Susceptibility Female Fundamental and applied biological sciences. Psychology Gas, fumes Gene Function Genetic Linkage Genetic Markers Genetics of eukaryotes. Biological and molecular evolution Genotype Human Genetics letter Lung - drug effects Lung - pathology Male Medical sciences Mice Mice, Inbred A Mice, Inbred C57BL Mice, Inbred CBA Mice, Inbred DBA Microsatellite Repeats Ozone - toxicity Quantitative Trait, Heritable Respiratory Hypersensitivity - chemically induced Respiratory Hypersensitivity - genetics Respiratory Hypersensitivity - mortality Respiratory Hypersensitivity - pathology Survival Analysis Toxicology Vertebrata
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