Alteration of Racial Differences in Melanosome Distribution in Human Epidermis after Exposure to Ultraviolet Light
CAREFUL studies of human epidermis have revealed that there is no significant difference between the number of melanocytes in the various racial groups, although there are regional differences in the population density of DOPA-positive melanocytes in various areas of the body (for example, on the fo...
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| Veröffentlicht in: | Nature. New biology (London) 1972-04, Vol.236 (66), p.143-145 |
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| container_title | Nature. New biology (London) |
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| creator | TODA, KIYOSHI PATHAK, MADHUKAR A. PARRISH, JOHN A. FITZPATRICK, THOMAS B. QUEVEDO, WALTER C. |
| description | CAREFUL studies of human epidermis have revealed that there is no significant difference between the number of melanocytes in the various racial groups, although there are regional differences in the population density of DOPA-positive melanocytes in various areas of the body (for example, on the forehead, 2,310 mm
−2
; abdomen, 800 mm
−2
; and back, 1,100 mm
−2
)
1
. These differences in the number of melanocytes may explain the colour differences in various areas of the body, but the colour of skin in the various races is apparently due to variations in the number of melanin granules, or melanosomes, in the melanocytes and in the epidermal keratinocytes, as well as to the degree of melanization of the individual melanosomes. |
| doi_str_mv | 10.1038/newbio236143a0 |
| format | Article |
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−2
; abdomen, 800 mm
−2
; and back, 1,100 mm
−2
)
1
. These differences in the number of melanocytes may explain the colour differences in various areas of the body, but the colour of skin in the various races is apparently due to variations in the number of melanin granules, or melanosomes, in the melanocytes and in the epidermal keratinocytes, as well as to the degree of melanization of the individual melanosomes.</description><identifier>ISSN: 0090-0028</identifier><identifier>EISSN: 2058-1092</identifier><identifier>DOI: 10.1038/newbio236143a0</identifier><identifier>PMID: 4502818</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>African Continental Ancestry Group ; Asian Continental Ancestry Group ; Benzofurans - pharmacology ; Biomedical and Life Sciences ; Buttocks ; Continental Population Groups ; Epithelium - radiation effects ; European Continental Ancestry Group ; Humans ; letters-to-editor ; Life Sciences ; Melanocytes - cytology ; Melanocytes - radiation effects ; Microscopy, Electron ; Microsomes - radiation effects ; Photosensitivity Disorders - chemically induced ; Skin - cytology ; Skin - radiation effects ; Ultraviolet Rays</subject><ispartof>Nature. New biology (London), 1972-04, Vol.236 (66), p.143-145</ispartof><rights>Springer Nature Limited 1972</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-68410dc8ccb7241d45f41417d9726cf101bb85be80b8edc74343068965b5fea33</citedby><cites>FETCH-LOGICAL-c396t-68410dc8ccb7241d45f41417d9726cf101bb85be80b8edc74343068965b5fea33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4502818$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>TODA, KIYOSHI</creatorcontrib><creatorcontrib>PATHAK, MADHUKAR A.</creatorcontrib><creatorcontrib>PARRISH, JOHN A.</creatorcontrib><creatorcontrib>FITZPATRICK, THOMAS B.</creatorcontrib><creatorcontrib>QUEVEDO, WALTER C.</creatorcontrib><title>Alteration of Racial Differences in Melanosome Distribution in Human Epidermis after Exposure to Ultraviolet Light</title><title>Nature. New biology (London)</title><addtitle>Nature New Biology</addtitle><addtitle>Nat New Biol</addtitle><description>CAREFUL studies of human epidermis have revealed that there is no significant difference between the number of melanocytes in the various racial groups, although there are regional differences in the population density of DOPA-positive melanocytes in various areas of the body (for example, on the forehead, 2,310 mm
−2
; abdomen, 800 mm
−2
; and back, 1,100 mm
−2
)
1
. These differences in the number of melanocytes may explain the colour differences in various areas of the body, but the colour of skin in the various races is apparently due to variations in the number of melanin granules, or melanosomes, in the melanocytes and in the epidermal keratinocytes, as well as to the degree of melanization of the individual melanosomes.</description><subject>African Continental Ancestry Group</subject><subject>Asian Continental Ancestry Group</subject><subject>Benzofurans - pharmacology</subject><subject>Biomedical and Life Sciences</subject><subject>Buttocks</subject><subject>Continental Population Groups</subject><subject>Epithelium - radiation effects</subject><subject>European Continental Ancestry Group</subject><subject>Humans</subject><subject>letters-to-editor</subject><subject>Life Sciences</subject><subject>Melanocytes - cytology</subject><subject>Melanocytes - radiation effects</subject><subject>Microscopy, Electron</subject><subject>Microsomes - radiation effects</subject><subject>Photosensitivity Disorders - chemically induced</subject><subject>Skin - cytology</subject><subject>Skin - radiation effects</subject><subject>Ultraviolet Rays</subject><issn>0090-0028</issn><issn>2058-1092</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1LxDAQhoMo67p69SbkD3R30qRtelzW9QNWBHHPJUknGmmbJWn9-PdWVwQPngbmmfeBeQk5ZzBnwOWiwzftfMpzJriCAzJNIZMJgzI9JFOAEhKAVB6TkxhfADgTRTohE5GNSyanJCybHoPqne-ot_RBGacaeumsxYCdwUhdR--wUZ2PvsWRxD44PXwHRnQztKqj652rMbQuUmVHHV2_73wcAtLe023TB_XqfIM93bin5_6UHFnVRDz7mTOyvVo_rm6Szf317Wq5SQwv8z7JpWBQG2mMLlLBapFZwQQr6rJIc2MZMK1lplGCllibQnDBIZdlnunMouJ8RuZ7rwk-xoC22gXXqvBRMai-uqv-djcGLvaB3aBbrH_Pf8oa-WLP40i6JwzVix9CN_7wn_ETNtZ87w</recordid><startdate>19720405</startdate><enddate>19720405</enddate><creator>TODA, KIYOSHI</creator><creator>PATHAK, MADHUKAR A.</creator><creator>PARRISH, JOHN A.</creator><creator>FITZPATRICK, THOMAS B.</creator><creator>QUEVEDO, WALTER C.</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19720405</creationdate><title>Alteration of Racial Differences in Melanosome Distribution in Human Epidermis after Exposure to Ultraviolet Light</title><author>TODA, KIYOSHI ; PATHAK, MADHUKAR A. ; PARRISH, JOHN A. ; FITZPATRICK, THOMAS B. ; QUEVEDO, WALTER C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-68410dc8ccb7241d45f41417d9726cf101bb85be80b8edc74343068965b5fea33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>African Continental Ancestry Group</topic><topic>Asian Continental Ancestry Group</topic><topic>Benzofurans - pharmacology</topic><topic>Biomedical and Life Sciences</topic><topic>Buttocks</topic><topic>Continental Population Groups</topic><topic>Epithelium - radiation effects</topic><topic>European Continental Ancestry Group</topic><topic>Humans</topic><topic>letters-to-editor</topic><topic>Life Sciences</topic><topic>Melanocytes - cytology</topic><topic>Melanocytes - radiation effects</topic><topic>Microscopy, Electron</topic><topic>Microsomes - radiation effects</topic><topic>Photosensitivity Disorders - chemically induced</topic><topic>Skin - cytology</topic><topic>Skin - radiation effects</topic><topic>Ultraviolet Rays</topic><toplevel>online_resources</toplevel><creatorcontrib>TODA, KIYOSHI</creatorcontrib><creatorcontrib>PATHAK, MADHUKAR A.</creatorcontrib><creatorcontrib>PARRISH, JOHN A.</creatorcontrib><creatorcontrib>FITZPATRICK, THOMAS B.</creatorcontrib><creatorcontrib>QUEVEDO, WALTER C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Nature. New biology (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>TODA, KIYOSHI</au><au>PATHAK, MADHUKAR A.</au><au>PARRISH, JOHN A.</au><au>FITZPATRICK, THOMAS B.</au><au>QUEVEDO, WALTER C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Alteration of Racial Differences in Melanosome Distribution in Human Epidermis after Exposure to Ultraviolet Light</atitle><jtitle>Nature. New biology (London)</jtitle><stitle>Nature New Biology</stitle><addtitle>Nat New Biol</addtitle><date>1972-04-05</date><risdate>1972</risdate><volume>236</volume><issue>66</issue><spage>143</spage><epage>145</epage><pages>143-145</pages><issn>0090-0028</issn><eissn>2058-1092</eissn><abstract>CAREFUL studies of human epidermis have revealed that there is no significant difference between the number of melanocytes in the various racial groups, although there are regional differences in the population density of DOPA-positive melanocytes in various areas of the body (for example, on the forehead, 2,310 mm
−2
; abdomen, 800 mm
−2
; and back, 1,100 mm
−2
)
1
. These differences in the number of melanocytes may explain the colour differences in various areas of the body, but the colour of skin in the various races is apparently due to variations in the number of melanin granules, or melanosomes, in the melanocytes and in the epidermal keratinocytes, as well as to the degree of melanization of the individual melanosomes.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>4502818</pmid><doi>10.1038/newbio236143a0</doi><tpages>3</tpages></addata></record> |
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| subjects | African Continental Ancestry Group Asian Continental Ancestry Group Benzofurans - pharmacology Biomedical and Life Sciences Buttocks Continental Population Groups Epithelium - radiation effects European Continental Ancestry Group Humans letters-to-editor Life Sciences Melanocytes - cytology Melanocytes - radiation effects Microscopy, Electron Microsomes - radiation effects Photosensitivity Disorders - chemically induced Skin - cytology Skin - radiation effects Ultraviolet Rays |
| title | Alteration of Racial Differences in Melanosome Distribution in Human Epidermis after Exposure to Ultraviolet Light |
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