Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration

Phosphoinositide 3-kinase: Role of the p110a isoform The p110α isoform of phosphoinositide 3-kinase is shown to play a critical role in normal and pathological angiogenesis. In particular, it is needed to mediate the migration of endothelial cells downstream of VEGF receptor activation, acting upstr...

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Veröffentlicht in:	Nature (London) 2008-05, Vol.453 (7195), p.662-666
Hauptverfasser:	Graupera, Mariona, Guillermet-Guibert, Julie, Foukas, Lazaros C., Phng, Li-Kun, Cain, Robert J., Salpekar, Ashreena, Pearce, Wayne, Meek, Stephen, Millan, Jaime, Cutillas, Pedro R., Smith, Andrew J. H., Ridley, Anne J., Ruhrberg, Christiana, Gerhardt, Holger, Vanhaesebroeck, Bart
Format:	Artikel
Sprache:	eng
Schlagworte:	Humanities and Social Sciences letter multidisciplinary Science Science (multidisciplinary)
Online-Zugang:	Volltext
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