A genetic variant of hypoxia-inducible factor-1α is associated with adverse outcomes in acute kidney injury

Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that mediates many cellular responses to tissue hypoxia, a common feature of acute kidney injury (AKI). Here we studied 241 patients with AKI and determined the relationship to adverse outcome of a non-synonymous polymorphism in the codi...

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Veröffentlicht in:	Kidney international 2009-06, Vol.75 (12), p.1322-1329
Hauptverfasser:	Kolyada, Alexey Y., Tighiouart, Hocine, Perianayagam, Mary C., Liangos, Orfeas, Madias, Nicolaos E., Jaber, Bertrand L.
Format:	Artikel
Sprache:	eng
Schlagworte:	acute kidney injury angiopoietin-2 Biological and medical sciences gene polymorphism HIF-1α Kidneys Medical sciences Nephrology. Urinary tract diseases Urinary system involvement in other diseases. Miscellaneous VEGF-A
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