TGF-β1-induced cell cycle arrest in renal mesangial cells involves inhibition of cyclin E-cdk 2 activation and retinoblastoma protein phosphorylation

TGF-β1-induced cell cycle arrest in renal mesangial cells involves inhibition of cyclin E-cdk 2 activation and retinoblastoma protein phosphorylation. In glomerular disease, transforming growth factor-β1 (TGF-β1) has been demonstrated to exert anti-mitogenic and anti-inflammatory as well as fibrogen...

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Veröffentlicht in:Kidney international 1997-04, Vol.51 (4), p.1228-1236
Hauptverfasser: Schoecklmann, Harald O., Rupprecht, Harald D., Zauner, Ira, Sterzel, R. Bernd
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Sprache:eng
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