Circulating human pituitary pro-γ-melanotropin enhances the adrenal response to ACTH

The amino-terminal region of the common corticotropin/ β -lipotropin ( β -LPH) precursor has been identified in the AtT-20 mouse tumour cell as a glycopeptide with an apparent molecular weight of 16,000 (the ‘16K fragment’) 1,2 A third melanotropin core sequence or γ -MSH similar to that found in AC...

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