Superoxide involvement in the bactericidal effects of negative air ions on Staphylococcus albus
The physical nature of small air ions is well established and it is recognised that they can produce a variety of biological effects 1 . However, in only a few instances have any underlying biochemical changes been detected 2–4 . Theoretically, one can consider the hydrated Superoxide radical anion...
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| Veröffentlicht in: | Nature (London) 1979-10, Vol.281 (5730), p.400-401 |
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| creator | Kellogg, E. W Yost, M. G Barthakur, N Kreuger, A. P |
| description | The physical nature of small air ions is well established and it is recognised that they can produce a variety of biological effects
1
. However, in only a few instances have any underlying biochemical changes been detected
2–4
. Theoretically, one can consider the hydrated Superoxide radical anion (O
2
−
) (H
2
O)
n
with
n
≃4–8 as a likely candidate for a biologically active species of negative air ion
5
. The chemical and biological reactivity of Superoxide is high
6
and includes a leading role in bacterial killing caused by radiation
7,8
, in which Superoxide dismutase (SOD), an enzyme that catalyses the reaction: O
2
−
+O
2
−
2H→H
2
O
2
+O
2
protected markedly. Other studies have also demonstrated the bactericidal effect of O
2
−
(refs 9–11). Inasmuch as the bactericidal action of small negative air ions has been repeatedly confirmed, we decided to test for the involvement of O
2
−
in this phenomenon by evaluating the protective effect of SOD. Our results show strong O
2
−
involvement in negative air ion bacterial kill. |
| doi_str_mv | 10.1038/281400a0 |
| format | Article |
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1
. However, in only a few instances have any underlying biochemical changes been detected
2–4
. Theoretically, one can consider the hydrated Superoxide radical anion (O
2
−
) (H
2
O)
n
with
n
≃4–8 as a likely candidate for a biologically active species of negative air ion
5
. The chemical and biological reactivity of Superoxide is high
6
and includes a leading role in bacterial killing caused by radiation
7,8
, in which Superoxide dismutase (SOD), an enzyme that catalyses the reaction: O
2
−
+O
2
−
2H→H
2
O
2
+O
2
protected markedly. Other studies have also demonstrated the bactericidal effect of O
2
−
(refs 9–11). Inasmuch as the bactericidal action of small negative air ions has been repeatedly confirmed, we decided to test for the involvement of O
2
−
in this phenomenon by evaluating the protective effect of SOD. Our results show strong O
2
−
involvement in negative air ion bacterial kill.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/281400a0</identifier><identifier>PMID: 225679</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Anions ; Atmosphere ; Humanities and Social Sciences ; letter ; multidisciplinary ; Oxygen - toxicity ; Science ; Science (multidisciplinary) ; Staphylococcus - drug effects ; Superoxides - toxicity</subject><ispartof>Nature (London), 1979-10, Vol.281 (5730), p.400-401</ispartof><rights>Springer Nature Limited 1979</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c434t-7948623cbbe20479d51659c2985253c58d3d48195bd9129e54e594db012923043</citedby><cites>FETCH-LOGICAL-c434t-7948623cbbe20479d51659c2985253c58d3d48195bd9129e54e594db012923043</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/281400a0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/281400a0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,2727,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/225679$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kellogg, E. W</creatorcontrib><creatorcontrib>Yost, M. G</creatorcontrib><creatorcontrib>Barthakur, N</creatorcontrib><creatorcontrib>Kreuger, A. P</creatorcontrib><title>Superoxide involvement in the bactericidal effects of negative air ions on Staphylococcus albus</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>The physical nature of small air ions is well established and it is recognised that they can produce a variety of biological effects
1
. However, in only a few instances have any underlying biochemical changes been detected
2–4
. Theoretically, one can consider the hydrated Superoxide radical anion (O
2
−
) (H
2
O)
n
with
n
≃4–8 as a likely candidate for a biologically active species of negative air ion
5
. The chemical and biological reactivity of Superoxide is high
6
and includes a leading role in bacterial killing caused by radiation
7,8
, in which Superoxide dismutase (SOD), an enzyme that catalyses the reaction: O
2
−
+O
2
−
2H→H
2
O
2
+O
2
protected markedly. Other studies have also demonstrated the bactericidal effect of O
2
−
(refs 9–11). Inasmuch as the bactericidal action of small negative air ions has been repeatedly confirmed, we decided to test for the involvement of O
2
−
in this phenomenon by evaluating the protective effect of SOD. Our results show strong O
2
−
involvement in negative air ion bacterial kill.</description><subject>Anions</subject><subject>Atmosphere</subject><subject>Humanities and Social Sciences</subject><subject>letter</subject><subject>multidisciplinary</subject><subject>Oxygen - toxicity</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Staphylococcus - drug effects</subject><subject>Superoxides - toxicity</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEtLw0AUhQfxVavgDxCZpS6i80xmllJ8QcFFdR0mMzftlDQJM0mx_95IrG5c3cf5OBwOQpeU3FHC1T1TVBBiyAGaUJGliUhVdogmhDCVEMXTU3QW45oQImkmTtAxYzLN9ATli76F0Hx6B9jX26bawgbqbthxtwJcGNtB8NY7U2EoS7BdxE2Ja1iazm8BGx-wb-rhWeNFZ9rVrmpsY20fsamKPp6jo9JUES5-5hR9PD2-z16S-dvz6-xhnljBRZdkWqiUcVsUwIjItJM0ldoyrSST3ErluBOKalk4TZkGKUBq4QoyHIwTwafoZvS1oYkxQJm3wW9M2OWU5N8N5fuGBvRqRNu-2ID7BcdKBvl2lOMg1EsI-brpQz2E_8_qemRr0_UB_qz2wBdM23c3</recordid><startdate>19791004</startdate><enddate>19791004</enddate><creator>Kellogg, E. W</creator><creator>Yost, M. G</creator><creator>Barthakur, N</creator><creator>Kreuger, A. P</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19791004</creationdate><title>Superoxide involvement in the bactericidal effects of negative air ions on Staphylococcus albus</title><author>Kellogg, E. W ; Yost, M. G ; Barthakur, N ; Kreuger, A. P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c434t-7948623cbbe20479d51659c2985253c58d3d48195bd9129e54e594db012923043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Anions</topic><topic>Atmosphere</topic><topic>Humanities and Social Sciences</topic><topic>letter</topic><topic>multidisciplinary</topic><topic>Oxygen - toxicity</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Staphylococcus - drug effects</topic><topic>Superoxides - toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kellogg, E. W</creatorcontrib><creatorcontrib>Yost, M. G</creatorcontrib><creatorcontrib>Barthakur, N</creatorcontrib><creatorcontrib>Kreuger, A. P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kellogg, E. W</au><au>Yost, M. G</au><au>Barthakur, N</au><au>Kreuger, A. P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Superoxide involvement in the bactericidal effects of negative air ions on Staphylococcus albus</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1979-10-04</date><risdate>1979</risdate><volume>281</volume><issue>5730</issue><spage>400</spage><epage>401</epage><pages>400-401</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>The physical nature of small air ions is well established and it is recognised that they can produce a variety of biological effects
1
. However, in only a few instances have any underlying biochemical changes been detected
2–4
. Theoretically, one can consider the hydrated Superoxide radical anion (O
2
−
) (H
2
O)
n
with
n
≃4–8 as a likely candidate for a biologically active species of negative air ion
5
. The chemical and biological reactivity of Superoxide is high
6
and includes a leading role in bacterial killing caused by radiation
7,8
, in which Superoxide dismutase (SOD), an enzyme that catalyses the reaction: O
2
−
+O
2
−
2H→H
2
O
2
+O
2
protected markedly. Other studies have also demonstrated the bactericidal effect of O
2
−
(refs 9–11). Inasmuch as the bactericidal action of small negative air ions has been repeatedly confirmed, we decided to test for the involvement of O
2
−
in this phenomenon by evaluating the protective effect of SOD. Our results show strong O
2
−
involvement in negative air ion bacterial kill.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>225679</pmid><doi>10.1038/281400a0</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Nature (London), 1979-10, Vol.281 (5730), p.400-401 |
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| language | eng |
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| source | MEDLINE; Nature; SpringerNature Journals |
| subjects | Anions Atmosphere Humanities and Social Sciences letter multidisciplinary Oxygen - toxicity Science Science (multidisciplinary) Staphylococcus - drug effects Superoxides - toxicity |
| title | Superoxide involvement in the bactericidal effects of negative air ions on Staphylococcus albus |
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