Bilayers containing gangliosides develop channels when exposed to cholera toxin

CHOLERA toxin, a protein of molecular weight 84,000, comprising five or six B and one A subunits, produces massive diarrhoea in man and other mammals by altering the transport of salt and water across the intestinal epithelium 1–4 . These effects are mediated by a sequence of events leading to an in...

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Veröffentlicht in:	Nature (London) 1978-09, Vol.275 (5676), p.142-144
Hauptverfasser:	TOSTESON, M. T, TOSTESON, D. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Cholera Toxin Electric Conductivity G(M1) Ganglioside Gangliosides Humanities and Social Sciences Ion Channels letter Macromolecular Substances Membranes, Artificial Models, Biological multidisciplinary Science Science (multidisciplinary)
Online-Zugang:	Volltext
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