Murine neuroblastoma cured in vivo by an antibody-dependent cellular cytotoxicity reaction

CYTOLYSIS of antibody-coated tumour cells mediated by reticuloendothelial (RE) or bone marrow cells is a phenomenon of unknown biological relevance 1–4 . The specificity of the reaction lies in the antibody 5,6 ; probably most or all cells able to recognise the Fc fragment of the antibody molecule c...

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Veröffentlicht in:	Nature (London) 1976-12, Vol.264 (5588), p.783-785
Hauptverfasser:	BYFIELD, JOHN E., ZERUBAVEL, RAQUEL, FONKALSRUD, ERIC W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Neoplasm - administration & dosage Cytotoxicity Tests, Immunologic Dose-Response Relationship, Immunologic Humanities and Social Sciences Immunization, Passive Immunotherapy letter Mice Mononuclear Phagocyte System - immunology multidisciplinary Neoplasms, Experimental - immunology Neoplasms, Experimental - therapy Neuroblastoma - immunology Neuroblastoma - therapy Science Science (multidisciplinary) Spleen - immunology
Online-Zugang:	Volltext
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