Demonstration of Endogenous Pyrogen in Serum during Systemic Tuberculin Reaction in Rabbits
SUBSTANCES capable of producing fever in normal recipients (the so-called endogenous pyrogens) appear in the serum of experimental animals during fever due to bacterial endotoxin, influenza virus and streptococcal and pneumococcal infections 1 . Systemic tuberculin reaction is very similar to the ef...
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| Veröffentlicht in: | Nature (London) 1959-03, Vol.183 (4662), p.693-694 |
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| container_title | Nature (London) |
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| creator | JOHANOVSKY, J |
| description | SUBSTANCES capable of producing fever in normal recipients (the so-called endogenous pyrogens) appear in the serum of experimental animals during fever due to bacterial endotoxin, influenza virus and streptococcal and pneumococcal infections
1
. Systemic tuberculin reaction is very similar to the effect of bacterial endotoxins
2
. An attempt has therefore been made to demonstrate the presence of substances with an effect corresponding to that of endogenous pyrogen in the serum of experimental rabbits during systemic tuberculin reaction. |
| doi_str_mv | 10.1038/183693a0 |
| format | Article |
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1
. Systemic tuberculin reaction is very similar to the effect of bacterial endotoxins
2
. An attempt has therefore been made to demonstrate the presence of substances with an effect corresponding to that of endogenous pyrogen in the serum of experimental rabbits during systemic tuberculin reaction.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/183693a0</identifier><identifier>PMID: 13632844</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Animals ; Humanities and Social Sciences ; Interleukin-1 ; letter ; multidisciplinary ; Pyrogens - blood ; Rabbits ; Science ; Science (multidisciplinary) ; Tuberculin ; Tuberculin Test</subject><ispartof>Nature (London), 1959-03, Vol.183 (4662), p.693-694</ispartof><rights>Springer Nature Limited 1959</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c315t-84bb6df9fd8bc67d44d4350a3ca80d1a2d311ff2321809ea766fda734ab754b63</citedby><cites>FETCH-LOGICAL-c315t-84bb6df9fd8bc67d44d4350a3ca80d1a2d311ff2321809ea766fda734ab754b63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/183693a0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/183693a0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13632844$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>JOHANOVSKY, J</creatorcontrib><title>Demonstration of Endogenous Pyrogen in Serum during Systemic Tuberculin Reaction in Rabbits</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>SUBSTANCES capable of producing fever in normal recipients (the so-called endogenous pyrogens) appear in the serum of experimental animals during fever due to bacterial endotoxin, influenza virus and streptococcal and pneumococcal infections
1
. Systemic tuberculin reaction is very similar to the effect of bacterial endotoxins
2
. An attempt has therefore been made to demonstrate the presence of substances with an effect corresponding to that of endogenous pyrogen in the serum of experimental rabbits during systemic tuberculin reaction.</description><subject>Animals</subject><subject>Humanities and Social Sciences</subject><subject>Interleukin-1</subject><subject>letter</subject><subject>multidisciplinary</subject><subject>Pyrogens - blood</subject><subject>Rabbits</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Tuberculin</subject><subject>Tuberculin Test</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1959</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkE1LAzEURYMotlbBXyBZ6mI0mWSSdClaP6Cg2LpyMeSzTOkkJZks-u-dsRUXrt6Fd7i8dwC4xOgWIyLusCBsSiQ6AmNMOSsoE_wYjBEqRYH63QicpbRGCFWY01MwwoSRUlA6Bl-Ptg0-dVF2TfAwODjzJqysDznB910cImw8XNiYW2hybPwKLnaps22j4TIrG3Xe9MCHlfqnYshSqaZL5-DEyU2yF4c5AZ9Ps-XDSzF_e359uJ8XmuCqKwRVihk3dUYozbih1FBSIUm0FMhgWRqCsXMlKbFAUys5Y85ITqhUvKKKkQm43vfqGFKK1tXb2LQy7mqM6sFP_eunR6_26Dar1po_8CCkB272QNoOr9pYr0OOvj__f9k33lNuPg</recordid><startdate>19590307</startdate><enddate>19590307</enddate><creator>JOHANOVSKY, J</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19590307</creationdate><title>Demonstration of Endogenous Pyrogen in Serum during Systemic Tuberculin Reaction in Rabbits</title><author>JOHANOVSKY, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c315t-84bb6df9fd8bc67d44d4350a3ca80d1a2d311ff2321809ea766fda734ab754b63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1959</creationdate><topic>Animals</topic><topic>Humanities and Social Sciences</topic><topic>Interleukin-1</topic><topic>letter</topic><topic>multidisciplinary</topic><topic>Pyrogens - blood</topic><topic>Rabbits</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Tuberculin</topic><topic>Tuberculin Test</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JOHANOVSKY, J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JOHANOVSKY, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Demonstration of Endogenous Pyrogen in Serum during Systemic Tuberculin Reaction in Rabbits</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1959-03-07</date><risdate>1959</risdate><volume>183</volume><issue>4662</issue><spage>693</spage><epage>694</epage><pages>693-694</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>SUBSTANCES capable of producing fever in normal recipients (the so-called endogenous pyrogens) appear in the serum of experimental animals during fever due to bacterial endotoxin, influenza virus and streptococcal and pneumococcal infections
1
. Systemic tuberculin reaction is very similar to the effect of bacterial endotoxins
2
. An attempt has therefore been made to demonstrate the presence of substances with an effect corresponding to that of endogenous pyrogen in the serum of experimental rabbits during systemic tuberculin reaction.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>13632844</pmid><doi>10.1038/183693a0</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1959-03, Vol.183 (4662), p.693-694 |
| issn | 0028-0836 1476-4687 |
| language | eng |
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| source | MEDLINE; SpringerLink (Online service); Nature Publishing Group |
| subjects | Animals Humanities and Social Sciences Interleukin-1 letter multidisciplinary Pyrogens - blood Rabbits Science Science (multidisciplinary) Tuberculin Tuberculin Test |
| title | Demonstration of Endogenous Pyrogen in Serum during Systemic Tuberculin Reaction in Rabbits |
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