Glutamatergic Agents in the Treatment of Compulsivity and Impulsivity in Child and Adolescent Psychiatry: a Systematic Review of the Literature

Research has implicated glutamatergic projections between the various frontal subregions in the pathogenesis of compulsivity and impulsivity. Reducing striatal glutamate release, or antagonising the action of glutamate at its receptors, may therefore represent viable treatment strategies. Several gl...

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Veröffentlicht in:	Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie 2018-05, Vol.46 (3), p.246-263
Hauptverfasser:	Mechler, Konstantin, Häge, Alexander, Schweinfurth, Nina, Glennon, Jeffrey C, Dijkhuizen, Rick M, Murphy, Declan, Durston, Sarah, Williams, Steven, K Buitelaar, Jan, Banaschewski, Tobias, Dittmann, Ralf W, Tactics Consortium, The
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine - adverse effects Acetylcysteine - therapeutic use Adolescent Attention Deficit Disorder with Hyperactivity - drug therapy Autism Spectrum Disorder - drug therapy Brain - drug effects Child Corpus Striatum - drug effects Excitatory Amino Acid Agents - adverse effects Excitatory Amino Acid Agents - therapeutic use Glutamic Acid - metabolism Humans Memantine - adverse effects Memantine - therapeutic use Obsessive-Compulsive Disorder - drug therapy Randomized Controlled Trials as Topic Receptors, Glutamate - drug effects Risk Assessment Treatment Outcome
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