Formation of 1,N 6-Etheno-2‘-deoxyadenosine Adducts by trans,trans-2,4-Decadienal

trans,trans-2,4-Decadienal (DDE) is an important breakdown product of lipid peroxidation. This aldehyde is cytotoxic to mammalian cells and is known to be implicated in DNA damage. Therefore, attempts were made in this work to assess the reactivity of DDE with 2‘-deoxyadenosine (dAdo). It was shown...

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Veröffentlicht in:	Chemical research in toxicology 1998-09, Vol.11 (9), p.1042-1047
Hauptverfasser:	Carvalho, Valdemir M, Di Mascio, Paolo, de Arruda Campos, Ivan P, Douki, Thierry, Cadet, Jean, Medeiros, Marisa H. G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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