Mercurial-Induced Hydrogen Peroxide Generation in Mouse Brain Mitochondria: Protective Effects of Quercetin

Plants of the genus Polygala have been shown to possess protective effects against neuronal death and cognitive impairments in neurodegenerative disorders related to excitotoxicity. Moreover, previous reports from our group have shown the neuroprotective effects of the plant Polygala paniculata agai...

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Veröffentlicht in:	Chemical research in toxicology 2007-12, Vol.20 (12), p.1919-1926
Hauptverfasser:	Franco, Jeferson L, Braga, Hugo C, Stringari, James, Missau, Fabiana C, Posser, Thais, Mendes, Beatriz G, Leal, Rodrigo B, Santos, Adair R. S, Dafre, Alcir L, Pizzolatti, Moacir G, Farina, Marcelo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - drug effects Brain - metabolism Glutathione - metabolism Hydrogen Peroxide - metabolism In Vitro Techniques Male Mercuric Chloride - toxicity Methylmercury Compounds - toxicity Mice Mitochondria - drug effects Mitochondria - metabolism Molecular Structure Neuroprotective Agents - isolation & purification Neuroprotective Agents - pharmacology Oxidation-Reduction Polygala - chemistry Quercetin - isolation & purification Quercetin - pharmacology
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