Comparison of Clinically Used and Experimental Iron Chelators for Protection against Oxidative Stress-Induced Cellular Injury

Iron imbalance plays an important role in oxidative stress associated with numerous pathological conditions. Therefore, iron chelation may be an effective therapeutic approach, but progress in this area is hindered by the lack of effective ligands. Also, the potential favorable effects of chelators...

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Veröffentlicht in:	Chemical research in toxicology 2010-06, Vol.23 (6), p.1105-1114
Hauptverfasser:	Bendova, Petra, Mackova, Eliska, Haskova, Pavlina, Vavrova, Anna, Jirkovsky, Eduard, Sterba, Martin, Popelova, Olga, Kalinowski, Danuta S, Kovarikova, Petra, Vavrova, Katerina, Richardson, Des R, Simunek, Tomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cell Survival - drug effects Cytoprotection - drug effects Iron Chelating Agents - chemistry Iron Chelating Agents - pharmacology Myocardium - cytology Oxidative Stress - drug effects tert-Butylhydroperoxide - pharmacology
Online-Zugang:	Volltext
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