Effect of Natural and Synthetic Estrogens on A549 Lung Cancer Cells: Correlation of Chemical Structures with Cytotoxic Effects

A series of synthetic (nonylphenol, diethylstilbestrol, and bisphenol A) and natural (quercetin, resveratrol, and genistein) phenolic estrogens were investigated for their ability to affect the viability and proliferation of A549 lung cancer cells. To assess and distinguish the cytotoxic effect of i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemical research in toxicology 2005-03, Vol.18 (3), p.466-474
Hauptverfasser:	Andreescu, Silvana, Sadik, Omowunmi A, McGee, Dennis W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - metabolism Adenocarcinoma - pathology Apoptosis - drug effects Cell Line, Tumor Cell Proliferation - drug effects Cell Survival - drug effects DNA Replication - drug effects DNA, Neoplasm - analysis DNA, Neoplasm - biosynthesis Dose-Response Relationship, Drug Estradiol Congeners - chemistry Estradiol Congeners - classification Estradiol Congeners - toxicity Estrogens, Non-Steroidal - chemistry Estrogens, Non-Steroidal - classification Estrogens, Non-Steroidal - toxicity Fluorescence Humans Lung Neoplasms - drug therapy Lung Neoplasms - metabolism Lung Neoplasms - pathology Phenols - chemistry Phenols - classification Phenols - toxicity Reproducibility of Results Structure-Activity Relationship Tetrazolium Salts Thiazoles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!