Development of a Manufacturing Process for Zatosetron Maleate

Zatosetron maleate is a potent, selective 5-hydroxytryptamine receptor antagonist. In anticipation of commercialization, a manufacturing synthesis of zatosetron from tropinone and 5-chlorosalicylic acid was developed. Development efforts focused on addressing several key issues including the supply...

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Veröffentlicht in:	Organic process research & development 1997-05, Vol.1 (3), p.198-210
Hauptverfasser:	Burks, John E, Espinosa, Leandro, LaBell, Elizabeth S, McGill, John M, Ritter, Allen R, Speakman, Jeffery L, Williams, MaryAnne, Bradley, David A, Haehl, Moira G, Schmid, Christopher R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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