Sonogashira Reactions with Propyne: Facile Synthesis of 4-Hydroxy-2-methylbenzofurans from Iodoresorcinols

The Sonogashira reaction of terminal alkynes and ortho-halophenols with subsequent cyclization is a well-precedented method for the synthesis of substituted benzofurans. Here we describe the extension of this method to the coupling of 2-iodoresorcinols and terminal alkynes, including propyne, to giv...

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Veröffentlicht in:	Organic process research & development 2010-01, Vol.14 (1), p.180-187
Hauptverfasser:	Berliner, Martin A, Cordi, Eric M, Dunetz, Joshua R, Price, Kristin E
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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