Improved Process for the Preparation of 6-Chloro-5-(2-chloroethyl)oxindole
The current process for ziprasidone involves preparation and isolation of the key intermediate 6-chloro-5-(2-chloroethyl)oxindole. An improved process for the synthesis of this intermediate is reported here. The new process involves use of a novel Lewis acid-mediated selective deoxygenation of the p...
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| Veröffentlicht in: | Organic process research & development 2008-11, Vol.12 (6), p.1142-1145 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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