Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix)

The recently discovered technique of deracemization by means of grinding a racemic conglomerate in contact with a solution wherein racemization occurs has been scaled up using an industrial bead mill to demonstrate the practical applicability. The time needed to reach the enantiopure end state is dr...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Organic process research & development 2010-07, Vol.14 (4), p.908-911
Hauptverfasser:	Noorduin, W. L, van der Asdonk, P, Bode, A. A. C, Meekes, H, van Enckevort, W. J. P, Vlieg, E, Kaptein, B, van der Meijden, M. W, Kellogg, R. M, Deroover, G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!