A Concise, Efficient and Production-Scale Synthesis of a Protected l-Lyxonolactone Derivative:  An Important Aldonolactone Core

A multikilogram-scale synthesis of l-lyxonolactone-2,3-O-isopropylidene is reported. It proceeds efficiently from an optimized, large-scale, aqueous bromine oxidation of d-ribose to d-ribonolactone including a one-pot isopropylidene formation, and subsequent conversion of the d-ribonolactone-2,3-O-i...

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Veröffentlicht in:Organic process research & development 2006-05, Vol.10 (3), p.484-486
Hauptverfasser: Batra, Hitesh, Moriarty, Robert M, Penmasta, Raju, Sharma, Vijay, Stanciuc, Gabriela, Staszewski, James P, Tuladhar, Sudersan M, Walsh, David A, Datla, Satyanarayana, Krishnaswamy, Sunderraj
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Sprache:eng
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