Ceftibuten: † Development of a Commercial Process Based on Cephalosporin C. Part IV. Pilot-Plant Scale Electrochemical Reduction of 3-Acetoxymethyl-7(R)-glutaroylaminoceph-3-em-4-carboxylic Acid 1(S)-Oxide

This contribution describes the operation of a pilot plant for the production of 3-exomethylene-7(R)-glutaroylaminocepham-4-carboxylic acid 1(S)-oxide (4a) by the electrochemical reduction of 3-acetoxymethyl-7(R)-glutaroylaminoceph-3-em-4-carboxylic acid 1(S)-oxide (3a). This conversion is a key ste...

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Veröffentlicht in:Organic process research & development 2002-03, Vol.6 (2), p.178-183
Hauptverfasser: Chai, Dennis, Genders, David, Weinberg, Norman, Zappi, Guillermo, Bernasconi, Ermanno, Lee, Junning, Roletto, Jacopo, Sogli, Loris, Walker, Derek, Martin, Charles R, Menon, Vinod, Zelenay, Piotr, Zhang, Haiyan
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Sprache:eng
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