First Highly Diastereoselective Synthesis of s yn α-Methyl β-Fluoroalkyl β-Amino Esters

A new two-step approach for the diastereoselective synthesis of the syn α-methyl β-fluoroalkyl β-amino esters 4 has been developed. This approach is based on the chemical reduction of the fluorinated β-enamino esters 3, which have been previously obtained from imidoyl chlorides 1 and lithium ester e...

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Veröffentlicht in:Organic letters 1999-10, Vol.1 (7), p.977-980
Hauptverfasser: Fustero, Santos, Pina, Belén, García de la Torre, Marta, Navarro, Antonio, Ramírez de Arellano, Carmen, Simón, Antonio
Format: Artikel
Sprache:eng
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