Bioactive Pyridoacridine Alkaloids from the Micronesian Sponge Oceanapia sp

The Micronesian sponge Oceanapia sp. afforded three pyridoacridine alkaloids: the known compounds kuanoniamine C (1) and kuanoniamine D (2), as well as the new N-deacyl derivative (3) of the kuanoniamines. Compounds 1 and 2 exhibited insecticidal activity toward neonate larvae of the polyphagous pe...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1998-02, Vol.61 (2), p.301-305
Hauptverfasser:	Eder, Claudia, Schupp, Peter, Proksch, Peter, Wray, Victor, Steube, Klaus, Müller, Christa E, Frobenius, Wolfram, Herderich, Markus, van Soest, Rob W. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acridines - isolation & purification Acridines - metabolism Acridines - pharmacology ADENOSINA ADENOSINE ALCALOIDE ALCALOIDES ALKALOIDS Alkaloids - isolation & purification Alkaloids - metabolism Alkaloids - pharmacology Animals Anti-Bacterial Agents Anti-Infective Agents - pharmacology Antineoplastic Agents - isolation & purification Antineoplastic Agents - metabolism Antineoplastic Agents - pharmacology Artemia Bacteria - drug effects BENZODIAZEPINES BINDING SITES Biological and medical sciences CHEMICAL COMPOSITION CHEMICAL STRUCTURE Cladosporium - drug effects COLORANT COLORANTES COMPOSE ORGANOAZOTE COMPOSICION QUIMICA COMPOSITION CHIMIQUE COMPUESTO ORGANICO DEL NITROGENO CONTROL DE INSECTOS CYTOTOXIC COMPOUNDS DERIVATIVES DOSAGE EFFECTS Drug Screening Assays, Antitumor DYES EFECTOS DE DOSIFICACION EFFET DOSE EPONGE ESPECTROMETRIA ESPONJAS ESTRUCTURA QUIMICA General pharmacology HeLa Cells Humans In Vitro Techniques INSECT CONTROL INSECTE NUISIBLE INSECTICIDAL PROPERTIES INSECTICIDAS INSECTICIDE INSECTICIDES Insecticides - pharmacology INSECTOS DANINOS KUANONIAMINE C KUANONIAMINE D LARVAE LARVAS LARVE LUTTE ANTIINSECTE Medical sciences Microbial Sensitivity Tests MICRONESIA EF MICRONESIA FS MICRONESIE EF Neostriatum - drug effects Neostriatum - metabolism ORGANIC NITROGEN COMPOUNDS PARAZOA PEST INSECTS Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Porifera - chemistry Rats Receptors, GABA-A - metabolism Receptors, Purinergic P1 - drug effects Receptors, Purinergic P1 - metabolism SPECTRAL ANALYSIS SPECTROMETRIE SPECTROMETRY SPODOPTERA LITTORALIS SPONGES STRUCTURE CHIMIQUE SUBSTANCE TOXIQUE SUSTANCIAS TOXICAS TOXIC SUBSTANCES
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