Nanocarrier-Mediated Inhibition of Macrophage Migration Inhibitory Factor Attenuates Secondary Injury after Spinal Cord Injury

Spinal cord injury (SCI) can lead to permanent motor and sensory deficits. Following the initial traumatic insult, secondary injury mechanisms characterized by persistent heightened inflammation are initiated and lead to continued and pervasive cell death and tissue damage. Anti-inflammatory drugs s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	ACS nano 2015-02, Vol.9 (2), p.1492-1505
Hauptverfasser:	Saxena, Tarun, Loomis, Kristin H, Pai, S. Balakrishna, Karumbaiah, Lohitash, Gaupp, Eric, Patil, Ketki, Patkar, Radhika, Bellamkonda, Ravi V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology Drug Carriers - chemistry Liposomes Macrophage Migration-Inhibitory Factors - antagonists & inhibitors Male Mice Nanostructures - chemistry Particle Size Polyethylene Glycols - chemistry Rats RAW 264.7 Cells Spinal Cord Injuries - complications Time Factors Trypan Blue - chemistry Trypan Blue - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!