DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

Many chemotherapeutics used for cancer treatments encounter issues during delivery to tumors in vivo and may have high levels of systemic toxicity due to their nonspecific distribution. Various materials have been explored to fabricate nanoparticles as drug carriers to improve delivery efficiency. H...

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Veröffentlicht in:	ACS nano 2014-07, Vol.8 (7), p.6633-6643
Hauptverfasser:	Zhang, Qian, Jiang, Qiao, Li, Na, Dai, Luru, Liu, Qing, Song, Linlin, Wang, Jinye, Li, Yaqian, Tian, Jie, Ding, Baoquan, Du, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacokinetics Antineoplastic Agents - pharmacology Cell Line, Tumor DNA - chemistry DNA - pharmacokinetics Drug Carriers - chemistry Drug Carriers - pharmacokinetics Drug Liberation Female Humans Mammary Neoplasms, Experimental - drug therapy Mammary Neoplasms, Experimental - metabolism Mammary Neoplasms, Experimental - pathology Mice Nanostructures - chemistry Tissue Distribution Xenograft Model Antitumor Assays
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