Left-Handed Helical Ribbon Intermediates in the Self-Assembly of a β-Sheet Peptide

We report the observation of intermediate structures in the self-assembly of the peptide KFE8 (FKFEFKFE), designed with alternating polar and nonpolar amino acids. Self-assembly was followed over time using atomic force microscopy (AFM), transmission electron microscopy (TEM), and circular dichroism...

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Veröffentlicht in:Nano letters 2002-04, Vol.2 (4), p.295-299
Hauptverfasser: Marini, Davide M, Hwang, Wonmuk, Lauffenburger, Douglas A, Zhang, Shuguang, Kamm, Roger D
Format: Artikel
Sprache:eng
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