Hybrid Periodic Mesoporous Organosilicas (PMO-SBA-16): A Support for Immobilization of d-Amino Acid Oxidase and Glutaryl-7-amino Cephalosporanic Acid Acylase Enzymes

This study examined the adsorption and stability of d-amino acid oxidase (DAAO) and glutaryl-7-amino cephalosporanic acid acylase (GL-7-ACA acylase) enzymes using two different types of periodic mesoporous organosilicas PMO-SBA-16 synthesized from 1,2-bis(trimethoxysilyl)ethane (BTME) and 1,4-bis(tr...

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Veröffentlicht in:Journal of physical chemistry. C 2012-05, Vol.116 (20), p.10904-10912
Hauptverfasser: Nohair, Bendaoud, Thao, Phan thi Hong, Nguyen, Vu Thi Hanh, Tien, Phi Quyet, Phuong, Dang Tuyet, Hy, Le Gia, Kaliaguine, Serge
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container_end_page 10912
container_issue 20
container_start_page 10904
container_title Journal of physical chemistry. C
container_volume 116
creator Nohair, Bendaoud
Thao, Phan thi Hong
Nguyen, Vu Thi Hanh
Tien, Phi Quyet
Phuong, Dang Tuyet
Hy, Le Gia
Kaliaguine, Serge
description This study examined the adsorption and stability of d-amino acid oxidase (DAAO) and glutaryl-7-amino cephalosporanic acid acylase (GL-7-ACA acylase) enzymes using two different types of periodic mesoporous organosilicas PMO-SBA-16 synthesized from 1,2-bis(trimethoxysilyl)ethane (BTME) and 1,4-bis(triethoxysilyl)benzene (BTEB). Very high loading, specific enzymatic activities, and stabilities have been reached by proper optimization of mesopore structure and morphology.
doi_str_mv 10.1021/jp2116998
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subjects Condensed matter: structure, mechanical and thermal properties
Exact sciences and technology
Physics
Solid surfaces and solid-solid interfaces
Surfaces and interfaces
thin films and whiskers (structure and nonelectronic properties)
title Hybrid Periodic Mesoporous Organosilicas (PMO-SBA-16): A Support for Immobilization of d-Amino Acid Oxidase and Glutaryl-7-amino Cephalosporanic Acid Acylase Enzymes
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