Structure of the First-Shell Active Site in Metallolactamase:  Effect of Water Ligands

In this study we have examined the behavior of the first-shell active site of metallolactamases as a function of water both bound directly as a zinc ligand and hydrogen bonded to protein-residue ligands in the active site and as a function of metal−metal distance. The inherent effective interaction...

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Veröffentlicht in:The journal of physical chemistry. B 2001-08, Vol.105 (33), p.8040-8049
Hauptverfasser: Krauss, M, Gilson, H. S. R, Gresh, N
Format: Artikel
Sprache:eng
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