Solution Phase Combinatorial Synthesis of Biaryl Libraries Employing Heterogeneous Conditions for Catalysis and Isolation with Size Exclusion Chromatography for Purification

A convenient and effective approach to the solution phase synthesis of biaryl libraries from iodoarenes is described enlisting 10% Pd−C as an inexpensive and readily available supported catalyst. Isolation and purification of small library mixtures, individual library members, and intermediates in t...

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Veröffentlicht in:	Journal of organic chemistry 1999-04, Vol.64 (7), p.2422-2427
Hauptverfasser:	Boger, Dale L, Goldberg, Joel, Andersson, Carl-Magnus
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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