d-Mannitol as the Chiral Source for the EPC Synthesis of Both Enantiomers of 3-Ethoxycarbonyl-4-hydroxy-2-isoxazolines and Highly Functionalized Tricyclic Systems

The EPC preparation of both enantiomers of cis- and trans 5-substituted 4-hydroxy-2-isoxazoline 2-oxides has been achieved in an enantiodivergent fashion starting from d-mannitol through the application of the tandem nitroaldol-cyclization reaction to enantiomerically pure α-mesyloxyaldehydes. These...

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Veröffentlicht in:	Journal of organic chemistry 1998-11, Vol.63 (23), p.8235-8246
Hauptverfasser:	Marotta, Emanuela, Baravelli, Marco, Maini, Luigi, Righi, Paolo, Rosini, Goffredo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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