Inter- and Intramolecular Differentiation of Enantiotopic Dioxane Acetals through Oxazaborolidinone-Mediated Enantioselective Ring-Cleavage Reaction:  Kinetic Resolution of Racemic 1,3-Alkanediols and Asymmetric Desymmetrization of M eso-1,3-polyols

Acetals derived from racemic 1,3-alkanediols undergo kinetic resolution in chiral oxazaborolidinone-mediated ring-cleavage reaction with nucleophiles such as enol silanes and allylic silanes. Enantioselectivity of the reaction is affected by nucleophiles, the N-sulfonyl groups of oxazaborolidinones,...

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Veröffentlicht in:	Journal of organic chemistry 2002-10, Vol.67 (20), p.7080-7090
Hauptverfasser:	Harada, Toshiro, Egusa, Takayuki, Igarashi, Yasuto, Kinugasa, Motoharu, Oku, Akira
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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