Design and Synthesis of Novel α 1 a Adrenoceptor-Selective Antagonists. 2. Approaches To Eliminate Opioid Agonist Metabolites via Modification of Linker and 4-Methoxycarbonyl-4-phenylpiperidine Moiety

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Veröffentlicht in:Journal of medicinal chemistry 1999-11, Vol.42 (23), p.4778-4793
Hauptverfasser: Murali Dhar, T. G., Nagarathnam, Dhanapalan, Marzabadi, Mohammad R., Lagu, Bharat, Wong, Wai C., Chiu, George, Tyagarajan, Sriram, Miao, Shou Wu, Zhang, Fengqi, Sun, Wanying, Tian, Dake, Shen, Quanrong, Zhang, Jack, Wetzel, John M., Forray, Carlos, Chang, Raymond S. L., Broten, Theodore P., Schorn, Terry W., Chen, Tsing Bao, O'Malley, Stacy, Ransom, Richard, Schneck, Kathryn, Bendesky, Robert, Harrell, Charles M., Vyas, Kamlesh P., Zhang, Kanyin, Gilbert, John, Pettibone, Douglas J., Patane, Michael A., Bock, Mark G., Freidinger, Roger M., Gluchowski, Charles
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container_end_page 4793
container_issue 23
container_start_page 4778
container_title Journal of medicinal chemistry
container_volume 42
creator Murali Dhar, T. G.
Nagarathnam, Dhanapalan
Marzabadi, Mohammad R.
Lagu, Bharat
Wong, Wai C.
Chiu, George
Tyagarajan, Sriram
Miao, Shou Wu
Zhang, Fengqi
Sun, Wanying
Tian, Dake
Shen, Quanrong
Zhang, Jack
Wetzel, John M.
Forray, Carlos
Chang, Raymond S. L.
Broten, Theodore P.
Schorn, Terry W.
Chen, Tsing Bao
O'Malley, Stacy
Ransom, Richard
Schneck, Kathryn
Bendesky, Robert
Harrell, Charles M.
Vyas, Kamlesh P.
Zhang, Kanyin
Gilbert, John
Pettibone, Douglas J.
Patane, Michael A.
Bock, Mark G.
Freidinger, Roger M.
Gluchowski, Charles
description
doi_str_mv 10.1021/jm990201h
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title Design and Synthesis of Novel α 1 a Adrenoceptor-Selective Antagonists. 2. Approaches To Eliminate Opioid Agonist Metabolites via Modification of Linker and 4-Methoxycarbonyl-4-phenylpiperidine Moiety
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